Premature Ejaculation Adult: 18-64 yr Initially, 30 mg approx. 1-3 hr before sexual activity, subsequent doses adjusted according to response. Max: 60 mg. Dose should not be taken more than once in 24 hr. Review treatment after 4 wk (6 doses) and at least 6 mthly thereafter. Hepatic Impairment: Moderate to severe: Contraindicated.